Pilot Trial of Intravenous Lipid Emulsion Treatment for Severe Nifedipine-Induced Shock

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Failure of Intravenous Lipid Emulsion to Reduce Diazinon-induced Acute Toxicity: a Pilot Study in Rats

  Diazinon (DZN) is a synthetic organophosphorus (OPs) insecticide widely used in agricultural and household applications. OPs, particularly DZN, are highly lipid soluble liquids. Intravenous lipid emulsion (ILE) has been shown to reduce toxicity caused by some lipid soluble agents. We evaluated the antidote effect of ILE on acute toxicity of DZN. Twenty-four Sprague-Dawley female rats weightin...

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Failure of Intravenous Lipid Emulsion to Reduce Diazinon-induced Acute Toxicity: a Pilot Study in Rats

  Diazinon (DZN) is a synthetic organophosphorus (OPs) insecticide widely used in agricultural and household applications. OPs, particularly DZN, are highly lipid soluble liquids. Intravenous lipid emulsion (ILE) has been shown to reduce toxicity caused by some lipid soluble agents. We evaluated the antidote effect of ILE on acute toxicity of DZN. Twenty-four Sprague-Dawley female rats weightin...

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Treatment of Severe Carbamazepine Intoxication with Intravenous Lipid Emulsion Therapy

Carbamazepine (CBZ) is a widely prescribed anticonvulsant agent. It is used in treatment of epilepsy including general tonic-clonic, simple partial and complex partial seizures, neuropathicpains, especially in trigeminalneuralgia, central diabetes insipidus, attention-deficit and hyperactivity disorders and bipolar disorders. CBZ overdose is usually associated with cardiac, neurologic and respi...

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failure of intravenous lipid emulsion to reduce diazinon-induced acute toxicity: a pilot study in rats

diazinon (dzn) is a synthetic organophosphorus (ops) insecticide widely used in agricultural and household applications. ops, particularly dzn, are highly lipid soluble liquids. intravenous lipid emulsion (ile) has been shown to reduce toxicity caused by some lipid soluble agents. we evaluated the antidote effect of ile on acute toxicity of dzn. twenty-four sprague-dawley female rats weighting ...

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Intravenous lipid emulsion for treatment of local anesthetic toxicity

CLINICAL QUESTION Is intravenous lipid emulsion a safe and effective therapy for the reversal and treatment of local anesthetic toxicity? RESULTS Systematic reviews, human case reports, and experimental animal studies have demonstrated the efficacy of intravenous lipid emulsion therapy in successfully reversing cardiac arrhythmias, cardiac arrest, and cardiac collapse seen with severe systemi...

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ژورنال

عنوان ژورنال: Journal of Medical Toxicology

سال: 2016

ISSN: 1556-9039,1937-6995

DOI: 10.1007/s13181-016-0572-6